The Isfahan Cohort Study (ICS) was a population-based, longitudinal study of 6504 adults aged 35 years old or more. The subjects were recruited from urban and rural areas of three districts in central Iran consisting of Isfahan, Najafabad, and Arak from January to September 2001. The participants were followed biannually in order to detect major cardiovascular events including myocardial infarction, unstable angina pectoris, stroke, and sudden cardiac death until 2011. Baseline laboratory and clinical measurements were repeated in 2007; and for a subsample in 2013.



  • To map the Iranian cardiovascular risk chart that indicates the CVD relative risk for each risk factor or combination of some of them
  • To investigate the association of various life style behaviour, anthropometric measurements, and biochemical markers with the risk of CVD events
  • To evaluate relationships of factor associated with incident CVD risk factors